Searchable abstracts of presentations at key conferences on reproductive biology and medicine

ra0001p211 | (1) | WCRB2014

The role of the molecular chaperone HSPA2 in unexplained failure of IVF

Nixon Brett , Bromfield Elizabeth , Redgrove Kate , Baker Mark A , Aitken Robert John

Introduction: A common defect encountered in the spermatozoa of male infertility patients is an idiopathic failure of sperm–egg recognition. The aim of this study was to investigate the molecular basis of this condition.Materials and methods: For the purpose of this study we compared the proteomic profiles of spermatozoa from male infertility patients exhibiting an impaired capacity for sperm–egg recognition with that of sperm from males of pro...